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Expert views

Sustainable, cost-efficient manufacturing of therapeutic peptides using chemo-enzymatic peptide synthesis (CEPS)

22 Nov 2019 - Using a large scale biocatalytic manufacture of the antidiabetic exenatide as an example, we report that chemo-enzymatic peptide synthesis (CEPS) constitutes an efficient method for sustainable manufacturing of therapeutic peptides. […]

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Expert views

ReGreen SPPS: enabling circular chemistry in environmentally sensible solid-phase peptide synthesis

15 Oct 2019 - Aiming at greener, scalable methods for cost-efficient peptide synthesis a solid-phase peptide synthesis (SPPS) protocol adhering to the principles of circular chemistry[…]

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Expert views

2D green SPPS: green solvents for on-resin removal of acid sensitive protecting groups and lactamization

15 May 2019 - Aiming at greener synthesis of complex peptides we report that conventional one-dimensional (1D) green solid-phase peptide synthesis (SPPS) is elevated to a two-dimensional (2D) concept […]

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