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PolyPeptide showcases leadership in sustainable peptide manufacturing with two landmark publications
19 Dec 2025 - The future of peptide manufacturing isn’t just about making more—it’s about making better. Peptide therapeutics are transforming medicine, but traditional production can be resource-intensive. At PolyPeptide, […]
Read morePolyPeptide’s Approach to Process Intensification: Tackling the increasing Peptide Demand
27 Nov 2025 - Presented at TIDES Europe, 12 November 2025 Speaker: Francesco Terzani, Scientist Innovation Abstract: The global rise in peptide demand, driven by accelerated clinical development and speed to […]
Read moreBackbone Protecting Groups for Enhanced Peptide and Protein Synthesis
13 Aug 2025 - This review provides a comprehensive account of the use of backbone N-protecting groups in peptide synthesis. It includes detailed synthetic methods relating to their introduction and removal […]
Read moreExpanding the Reach of Sustainable Solid-Phase Peptide Synthesis
2 Apr 2025 - Alloc protecting group expanded the peptide synthesis toolbox. Its removal can sometimes be seen as an issue: toxic solvents, air-sensitive Pd0) reagents, challenging upscaling. Not anymore […]
Read moreImpurities in Peptide Drug Substance and Challenges Faced during Registration (in US, EU, Brazil and China Markets) and Commercial Phase
20 Mar 2025 - Controlling impurities in complex drug substances is a crucial part of development and due to lack of harmonized approaches from Health authorities, the manufacturer faces many […]
Read morePeptide Manufacturing: Rethinking the Technology Platform for Large Scale Demand
13 Nov 2024 - Presented at TIDES Europe, November 13, 2024 Speaker: Jan Pawlas, Scientist Global Development Abstract: The peptide market is strongly impacted by the evolution of the development pipeline, […]
Read morePolyPeptide supports landmark publication on sustainable peptide synthesis
23 Oct 2024 - PolyPeptide’s experts Jan Pawlas and Jon Holbech Rasmussen contributed to the recent landmark publication by UK’s Royal Society of Chemistry: “Sustainability in Tides Chemistry: Green Approaches […]
Read moreResearch article: Sustainable PFAS-free alternatives for TFA in SPPS
9 Aug 2024 - With growing manufacturing volumes, PolyPeptide remains dedicated to applying relevant principles of green chemistry. We are proud of our scientists pushing the frontiers and actively contributing […]
Read moreAdvancing Sustainable Peptide Synthesis by Solvent Quality Control: Understanding and Mitigating Hydroperoxide in 1-Butyl-2-pyrrolidinone (NBP)
25 Jul 2024 - Org. Process Res. Dev. 2024, 28, 3347–3367 Pawlas, J.; Mohy El-Dine, T.; von Bargen, K.; von Bargen, C.; Nilsson, J.; Ludemann-Hombourger, O.; Rasmussen, J. H. See […]
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